Stereochemistry Part 2 Solutions: #14
14.* (1994 1 6) Two structures for thalidmoide are shown below.
A. Which of the following terms describe these substances: Enantiomers and optically active. B. Designate each of these compounds as R or S.
C. How many sites of unsaturation are found in thalidomide? Identify these. 10 sites of unsaturation: 3 alkene groups ( C=C ) 4 carbonyls ( C=O ) 3 rings D. Are there any aromatic groups in thalidomide? Explain. The six-membered ring with alternating pi bonds is aromatic -continuous cycle of oriented p orbitals -6 pi electrons The other rings in the structure are not aromatic. |
